According to the National Institutes of Health, scleroderma is a rare disease, which affects between 50 to 300 people per million. Scleroderma is divided into numerous categories, each with its own set of symptoms. Some people will just have mild skin irritations, while others will have a life-threatening condition.
When the immune system attacks connective tissue, it results in excessive collagen production. Collagen is a protein that is required to maintain the health and suppleness of connective tissue. When the body creates too much collagen, however, it can lead to fibrosis, a sort of scarring.
This fibrosis affects the skin in mild forms of scleroderma, generating rigid, thicker patches. However, it can also harm the internal organs and blood vessels in more severe situations. The heart, lungs, kidneys, and esophagus are the organs most commonly affected by scleroderma. Scleroderma is usually treated using medications and physical therapy.
CBD For Scleroderma
CBD is one of the hundreds of active chemicals produced by the cannabis plant. Unlike THC, it has no psychoactive properties. It does, however, have a substantial effect on both the body and the mind. People have started utilizing CBD to ease the symptoms of a variety of disorders and to maintain their overall health in recent years.
Numerous studies have shown that CBD has anti-inflammatory properties that can help in reducing inflammation in the body. CBD is a cannabinoid, which means it interacts with the endocannabinoid system in the body (ECS). The ECS is a vital biological system that regulates mobility, memory, emotion, sensation, and several other functions of the body. Experts now suspect that the endocannabinoid system may play a role in scleroderma. Clinical experiments are being conducted all around the world to see if cannabinoids can help.
How Does CBD Help?
In addition to the endocannabinoid receptors, CBD could connect to various other receptors present in our body to control many problems. Like the Peroxisome proliferator-activated receptor (PPAR). Alpha, beta, and gamma are the three kinds of PPAR. When it comes to scleroderma, it’s all about the PPAR-gamma receptors.
Synthetic cannabinoids, as well as those found in the ECS, have been revealed to bind to these receptors. This compound’s combined impact appears to be the key to its ability to reduce fibrosis and collagen buildup, thereby controlling scleroderma and other such problems.